Recent Advances in Pharmacological Profile and Traditional Uses of Crotalaria Burhia

Authors

  • Muhammad Rahil Aslam First Department of Internal Medicine, Faculty of Medicine, University of Toyama, Toyama, Japan.
  • Sana Jabbar Laboratory of Cancer Biology and Immunology, Department of Pharmaceutical Sciences, Institute of Natural Medicine, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
  • Nazish Aslam Department of Botany, Faculty of Sciences, The Government Sadiq College Women University, Bahawalpur, Pakistan, 63100
  • Nimra Aslam Department of Botany, Faculty of Sciences, University of Agriculture, Faisalabad, Pakistan, 03802
  • Hafiz Muhammad Asif Faculty of Medicine and Allied Health Sciences, University College of Conventional Medicine, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan
  • Khalil Ahmad Faculty of Medicine and Allied Health Sciences, University College of Conventional Medicine, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan
  • Muhammad Shahid Sagheer Faculty of Medicine and Allied Health Sciences, University College of Conventional Medicine, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan
  • Muhammad Muddasar Saeed Department of Eastern Medicine, Faculty of Medical Sciences, Government College University of Faisalabad, 38000, Pakistan
  • Muhammad Wasim Aslam Javed Faculty of Medicine and Allied Health Sciences, University College of Conventional Medicine, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan

Keywords:

Herbal medicines, crotalaria burhia, ethnopharmacology, pharmacological properties

Abstract

Background: Treating various diseases through herbal medicines/plants has become a novel development in drug discovery. Crotalaria burhia Buch-Ham (C. burhia) belongs to the family Fabaceae and is a shrub that can be found in arid regions of the world and abundantly in Pakistan, India, and Afghanistan. The plant possesses a variety of medicinal aspects that are obtained from the leaves, branches, and roots.

Objective: This review aimed to provide extensive and concise information to the readers highlight its importance and may provide some future directions for further advancement for the exploration of the uncovered mechanism.

Methodology: We conducted an efficient literature search on various search engines, including Google Scholar, Pubmed, Scopus, Web of Science, and Science Direct. The study covers all the research articles published till 2021. The review focuses on the original research articles, reviews as well as minireviews.

Results: In traditional medicine, this medicinal plant has been shown to treat gout, pain and swellings, eczema, hydrophobia, wounds and cuts, infection, renal pain, and gastric disorders. There are numerous essential phytochemicals such as alkaloids, flavonoids, phenols, polyphenols, tannins, steroids, triterpenoids, anthraquinones, crotalarine, monocrotaline, croburhine, crosemperine, quercetins, and sitosterol are reported to contribute to the therapeutic activity. Pharmacologically, C. burhia exhibits antibacterial, anti-inflammatory, anti-tumor, hypotensive, vasorelaxant, cardio-depressant, diuretic potential, and antinociceptive properties, all of which support its traditional usage.

Conclusion: This broad perspective in the research exploring the pharmacological potential of C. burhia indeed supports its utilization in the past as a potential remedial agent to cure various skin and joint diseases.

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Published

2023-09-30

Issue

Vol. 1 No. 3 (2023): Volume 1 (3) 2023

Section

Articles